| 2007 | 2006 | 2005 | |
| 2004 | 2003 | 2002 | 2001 |
| 2000 | 1999 | 1998 | 1997 |
| 1996 | 1995 | 1994 | 1993 |
| 1992-87 |
2007 |
|
109. |
Luo, J.;
Pardin, C.; Lubell, W. D.; Zhu, X. X. “Poly(vinyl alcohol)-graft-poly(ethylene
glycol) resins and their use in solid-phase synthesis and supported TEMPO
catalysis”, Chem. Commun., 2007, 21, 2136-2138.Lien - Article - Link |
108. |
Dorr, A.;
Lubell, W. D. “Synthesis of a new
p-deficient
phenylalanine derivative from a common 1,4-diketone intermediate and study of
the influence of aromatic density on prolyl amide isomer population”,
Biopolymers, 2007, 88(2), 290-299.
Lien - Article - Link |
107. |
Boeglin,
D.; Hamdan, F. F.; Melendez, R. E.; Cluzeau, J.; Laperriere, A.; Heroux, M.;
Bouvier, M.; Lubell, W. D. “Calcitonin gene-related peptide analogues with
aza and indolizidinone amino acid residues reveal conformational requirements
for antagonist activity at the human calcitonin gene-related peptide 1 receptor”,
J. Med. Chem., 2007, 50(6), 1401-1408.
Lien - Article - Link
|
106. |
Rao, Mallem
H. V. R.; Pinyol, E.; Lubell, W. D. “Rigid dipeptide mimics: synthesis of
enantiopure C6-functionalized pyrrolizidinone amino acids”, J. Org. Chem.,
2007, 72(3), 736-743.
Lien - Article - Link
|
2006 |
|
105. |
Jolicoeur,
B.; Lubell, W. D. “4-Alkoxy- and 4-amino-2,2'-bipyrrole synthesis”,
Org. Lett., 2006, 8(26), 6107-6110.
Lien - Article - Link |
104. |
Jolicoeur,
B.; Chapman, E. E.; Thompson, A.; Lubell, W. D. “Pyrrole protection”,
Tetrahedron, 2006, 62(50), 11531-11563.
Lien - Article - Link |
103. |
Iden, H.
S.; Lubell, W. D. “1,4-Diazepinone and Pyrrolodiazepinone Syntheses via
Homoallylic Ketones from Cascade Addition of Vinyl Grignard Reagent to
a-Aminoacyl-b-amino
Esters”,
Org. Lett., 2006, 8(16), 3425-3428.
Lien - Article - Link
|
102. |
Surprenant,
S.; Lubell, William D. “From Macrocycle Dipeptide Lactams To
Azabicyclo[X.Y.0]alkanone Amino Acids: A Transannular Cyclization Route for
Peptide Mimic Synthesis”, Org. Lett., 2006, 8(13), 2851-2854.
Lien - Article - Link
|
101. |
Surprenant, S.; Lubell, W. D. "9-(4-Bromophenyl)-9-fluorenyl
as a Safety-Catch Nitrogen Protecting Group" J. Org. Chem. 2006, 71(2), 848-851.Lien - Article - Link |
100. |
Brouillette, Y.; Rombouts, F. J. R.; Lubell, W. D. "Solid-Phase Synthesis of
3-Aminopyrrole-2,5-dicarboxylate Analogs" J. Comb. Chem. 2006, 8(1), 117-126. Lien - Article - Link |
2005 |
|
99. |
Lubell, W.D., Blankenship, J.W., Fridkin, G., Kaul, R. (2005) Peptides. Science of Synthesis 21.11, Chemistry of Amides. Thieme, Stuttgart, 713-809. |
98. |
Hansford, K. A.; Guarin, S. A. P., Skene, W. G.; Lubell, W. D. "Bis(pyrrol-2-yl)arylenes from the Tandem
Bi-directional Addition of Vinyl Grignard Reagents to Aryldiesters"
J. Org. Chem. 2005, 70, 7996-8000. Lien - Article - Link |
97. |
Boeglin, D.; Lubell, W. D. "Aza-Amino Acid Scanning of Secondary Structure Suited for
Solid-Phase Peptide Synthesis with Fmoc Chemistry and Aza-Amino Acids with Heteroatomic Side-Chains"
J. Comb. Chem. 2005, 7(6), 864-878. Lien - Article - Link |
96. |
Fridkin, G.; Lubell, W. D. "Deazapurine solid-phase
synthesis: combinatorial synthesis of a library of N3, N5, C6 trisubstituted pyrrolo[3,2-d]pyrimidine d
erivatives on cross-linked polystyrene bearing a cysteamine linker"
J. Comb. Chem. 2005, 7(6), 977-986. Lien - Article - Link |
95. |
Rombouts, F. J. R.; Fridkin, G.; Lubell, W. D.
"Deazapurine solid-phase synthesis: construction of 3-substituted pyrrolo[3,2-d]pyrimidine-6-carboxylates on cross-linked polystyrene bearing a cysteamine linker"
J. Comb. Chem. 2005, 7(4), 589-598. Lien - Article - Link |
94. |
Kaul, R.; Surprenant, S. Lubell, W. D. "Systematic Study of the Synthesis of Macrocyclic Dipeptide β-Turn Mimics Possessing 8-, 9- and 10- Membered Rings by Ring Closing Metathesis"
J. Org. Chem. 2005, 70, 3838-3844 and addition/correction 2005, 70(12),
4901-4902. Lien - Article - Link and/et Lien - Correction - Link |
93. |
Galaud, F.; Lubell, W. D. "Homoserine-Derived Cyclic Sulfamidate as Chiral Educt for The Diversity Oriented Synthesis of Lactam-Bridged Dipeptides"
Biopolymers (Peptide Science) 2005, 80, 665-674. Lien - Article - Link |
92. |
Sajjadi, Z.; Lubell, W. D.
"Amino Acid-Azetidine Chimeras: Synthesis of Enantiopure 3-Substituted Azetidine-2-carboxylic Acids"
J. Peptide Res. 2005, 65(2), 298-310. Lien - Article - Link |
91. |
Dettwiler, J. E.; Lubell, W. D. "Synthesis and Application of L-N-Boc-N-methyl-β-hydroxyvaline in the Preparation of a Depsipeptide"
Can. J. Chem. 2005, 83, 793-800. Lien - Article - Link |
90. |
Bélec, L.;
Blankenship, J.W.; Lubell, W.D. "Examination of Structural Characteristics of the Potent Oxytocin Antagonists
[dPen1,Pen6]-OT and [dPen1,Pen6,5-tBuPro7]-OT by NMR,
Raman, CD Spectroscopy and Molecular Modeling."
J. Peptide Sci. 2005, 11, 365-378. Lien - Article - Link |
2004 |
|
89. |
Kaul, R.;
Brouillette, Y.; Sajjadi, Z.; Hansford, K.A.; Lubell, W.D. "Selective tert-Butyl Ester Deprotection in the
Presence of Acid Labile Protecting Groups with Use of ZnBr2." J. Org. Chem. 2004, 69, 6131-6133. Lien - Article - Link |
88. |
Gingras, K.;
Avedissian, H.; Thouin, E.; Boulanger, V.; Essagian, C.; McKerracher, L.; Lubell, W.D. "Synthesis and evaluation
of 4-(1-aminoalkyl)-N-(4-pyridyl)cyclohexanecarboxamides as Rho kinase inhibitors and neurite outgrowth promoters."
Bioorg. Med. Chem. Lett. 2004, 14, 4931-4934. Lien - Article - Link |
87. |
Van Cauwenberghe,
S.; Simonin, F.; Cluzeau, J.; Becker, J.A.J.; Lubell, W.D.; Tourwé, D. "Structure-Activity Study of the ORL1
Antagonist Ac-Arg-D-Cha-Qaa-D-Arg-D-p-ClPhe-NH2" J. Med. Chem. 2004, 47, 1864-1867. Lien - Article - Link |
86. |
Jeannotte, G.;
Lubell, W. D. "Large Structural Modification with Conserved Conformation: Analysis of Δ3- Fused Aryl Prolines in
Model β-Turns" J. Am. Chem. Soc. 2004, 126, 14334-14335. Lien - Article - Link |
85. |
Melendez, R.;
Lubell, W. D. "Aza-Amino Acid Scan for Rapid Identification of Secondary Structure Based on the Application of
N-Boc-Aza1-Dipeptides in Peptide Synthesis" J. Am. Chem. Soc. 2004, 126, 6759-6764. Lien - Article - Link |
84. |
Jeannotte, G.;
Lubell, W. D. "Synthesis of Fused Heteroarylprolines and Pyrrolopyrroles" J. Org. Chem. 2004, 69, 4656-4662. Lien - Article - Link |
83. |
Hansford, K. A.;
Zanzarova, V.; Dorr, A.; Lubell, W. D. "Three-Step Solution-Phase Combinatorial Access to 1,2-Disubstituted and
1,2,5-Trisubstituted Pyrroles from Carboxylic Esters" J. Combi. Chem. 2004, 6, 893-898. Lien - Article - Link |
82. |
Cluzeau, J; Lubell, W.D. "Conformationally Constrained Dipeptide Surrogates with Aromatic Side-Chains: Synthesis of 4-Aryl Indolizidin-9-one Amino Acids by Conjugate Addition to a Common α,ω-Diaminoazelate Enone Intermediate" J. Org. Chem. 2004, 69, 1504-1512. Lien - Article - Link |
81. |
Dettwiler, J.E.; Lubell, W.D. "Diversity-oriented synthesis of enantiopure N-protected β,β-dialkylserines" Can. J. Chem. 2004, 82, 318-324. Lien - Article - Link |
2003 |
|
80. |
Hansford, K.A.;Dettwiler, J.E.; Lubell, W.D. "One-Pot Synthesis of Homoallylic Ketones from the Addition of Vinyl Grignard Reagent to Carboxylic Esters" Org. Lett. 2003, 5, 4887-4890. Lien - Article - Link |
79. |
Dietrich, E.; Lubell, W. D. "Efficient synthesis of enantiopure pyrrolizidinone amino acid" J. Org. Chem. 2003, 68, 6988-6996. Lien - Article - Link |
78. |
Marcotte, F.A.; Rombouts, F.JR.; Lubell, W. D. "Diversity-oriented synthesis of functionalized pyrrolo[3,2-d]pyrimidines with variation of the pyrimidine ring nitrogen substituents" J. Org. Chem. 2003, 68, 6984-6987. Lien - Article - Link |
77. |
Meléndez, R.E.; Lubell, W.D. "Synthesis and Reactivity of Cyclic Sulfamidites and Sulfamidates" Tetrahedron 2003, 59, 2581-2616. Lien - Article - Link |
76. |
Dettwiler, J. E.; Lubell, W. D. "Serine as Chiral Educt for the Practical Synthesis of Enantiopure N-Protected β-Hydroxyvaline" J. Org. Chem. 2003, 68, 177-179. Lien - Article - Link |
2002 |
|
75. |
Krishna G. Peri, K.G.; Quiniou, C.; Hou X.; Abran, D.; Varma, D.R.; Lubell, W.D.; Chemtob, S. "HG113 : A Novel Selective FP Antagonist that Delays Preterms Labor" Seminars in Perinatology 2002, 26 (6), 389-397 |
74. |
Jeannotte, G.; Lubell, W. D. "Synthesis and Use of Pyrrol-Prolines for Peptide Mimicry." In Peptides 2002 (Proceedings of the 27th European Peptide Symposium), E. Benedetti, Editor, 206-207. |
73. |
Dietrich, E.; Lubell, W. D. "Il mondo é bello perché é vario, expanding azabicycloalkanone amino acid diversity. Efficient Synthesis of pyrrolizidinone amino acid" In Peptides 2002 (Proceedings of the 27th European Peptide Symposium), E. Benedetti, Editor, 202-203. |
72. |
Melendez, R. E.; Lubell, W. D. "Novel Approach for Enantiopure Azapeptide Synthesis: Application of N-Boc-Aza1-dipeptides in Solution- and Solid-Phase Peptide Chemistry" In Peptides 2002 (Proceedings of the 27th European Peptide Symposium), E. Benedetti, Editor, 204-205. |
71. |
HALAB,L.; BECKER, J. A. J.; DARULA, Z.; TOURWE, D.; KIEFFER, B. L.; SIMONIN, F.; LUBELL, W. D. "Probing Opioid Receptor Interactions with Azacycloalkane Amino Acids. Synthesis of a Potent and Selective ORL1 Antagonist" J. Med. Chem. 2002, 45, 5353-5357. Lien - Article - Link |
| 70. | Marcotte, F.-A.; Lubell, W. D. "An effective new synthesis of 4-aminopyrrole-2-carboxylates" Org. Lett. 2002, 4, 2601-2603. Lien - Article - Link |
69. |
Roy, S.; Lombart, H.-G.; Hancock, R.E.W.; Farmer, S.W.; Lubell, W.D. "Exploring Relationships Between Mimic Configuration, Peptide Conformation and Biological Activity in Indolizidin-2-one Amino Acid Analogs of Gramicidin S" J. Peptide Res. 2002, 60, 198-214. |
68. |
CLUZEAU, J.; LUBELL, W. D. "Remarkable Asymmetric Induction from Remote Stereocenters in Conjugate Addition Chemistry for the Synthesis of Alkyl-Branched α-ω-Diaminoazelates" Israel J. Chem. 2002, 41, 271-281. |
67. |
PERI, K.G.; QUINIOU, C.; HOU, X.; ABRAN, D.; VARMA, D.R.; LUBELL, W. D.; CHEMTOB, S. "THG113: a novel selective FP antagonist which delays preterm labor" Seminars in Perinatology 2002, 67, 389-397. |
66. |
DERGHAM, P.; ELLEZAM, B.; AVEDISSIAN, H.; ESSAGIAN, C.; LUBELL, W.D.; MCKERRACHER, L. "Rho signaling pathway targeted for spinal cord repair" J. Neurosci. 2002, 22, 6570-6577. |
65. |
MIRANDA, L. P.; LUBELL, W. D.; HALKES, K. M.; GROTH, T.; GRØTLI, M.; RADEMAN, J.; GOTFREDSEN, C. H.; MELDAL, M. "SPOCC 194, a New High Functional Group Density PEG-Based Resin for Solid-Phase Organic Synthesis "J. Combi. Chem. 2002, 4, 523-529. Lien - Article - Link |
64. |
HALAB,L.; Lubell, W. D. "Effect of Sequence on Peptide Geometry in 5-tert-Butylproline Type VI β-Turn Mimics " J. Am. Chem. Soc. 2002, 124, 2474-2484. Lien - Article - Link |
2001 |
|
63. |
Cluzeau, J.; Lubell, W. D. "Mimicry of the Backbone and Side-Chain Geometry of Peptides Turns: Synthesis of Novel 4-Substitued Indolizidin-9-one Amino Acids" In Peptides: Chem., Structure and Biology, M. Lebel and R. Houghten, Eds; ESCOM, Leiden, The Netherlands, 2001, 597-598. |
62. |
ROY, S.; LOMBART, H.-G.; FARMER, S.; HANCOCK, R.; LUBELL, W. D. "Exploring Relationships Between Antimicrobial Peptide Conformation and Biological Activity Using Indolizidinone Amino Acids. Synthesis of Potent Gramicidin S Analogs Having Reduced Hemolytic Activity" J. Peptide Res. in preparation. |
61. |
Atfani, M.; Wei, L.; Lubell, W. D. "N-(9-(9-Phenylfluorenyl))homoserine-Derived Cyclic Sulfamidates: Novel Chiral Educts for the Synthesis of Enantiopure γ-Substituted α-Amino Acids" Org. Lett. 2001; 3(19); 2965-2968. Lien - Article - Link |
60. |
BÉLEC, L.; SLANINOVA, J.; LUBELL, W. D. "The Influence of Steric Interactions on the Conformation and Biology Oxytocin. Synthesis and Analysis of Penicilamine6-Oxytocin and Penicilamine6-5-tert-Butylproline7-Oxytocin Analogues" J. Peptide Res. 2001, 58, 263-273. |
59. |
LUBELL, W. Book Review of "Solid-Phase Organic Synthesis by Kevin Burgess (Texas A & M University) Interscience: New York. 2000. " J. Am. Chem. Soc.; (Book Review) 2001, 123(27), 6744-6744. Lien - Article - Link |
58. |
HALAB,L.; BÉLEC, L.; LUBELL, W. D. "Improved Synthesis of (2S, 5S)-trans-5-tert-Butylproline" Tetrahedron 2001, 6439-6446. Lien - Article - Link |
57. |
POLYAK, F.; LUBELL, W. D. "Mimicry of Peptide Back-Bone Geometry and Heteroatomic Side-Chain Functionality : Synthesis of Enantiopure Indolizidin-2-one Amino Acids Possessing Alcohol, Acid and Amine Functional Groups" J. Org. Chem. 2001, 66, 1171-1180. Lien - Article - Link |
56. |
FENG, Z.; LUBELL, W. D. "Mimicry of Peptide Back-Bone Geometry and Heteroatomic Side-Chain Functionality: Synthesis of 7-[3-Azidopropyl]indolizidin-2-one Amino Acid as a Constrained Ala-Lys Dipeptide Surrogate" J. Org. Chem. 2001, 66, 1181-1185. Lien - Article - Link |
55. |
WEI, L.; LUBELL, W. D. "Scope and Limitations of N-(9-(9-Phenylfluorenyl))Serine-Derived Cyclic Sulfamidates in the Synthesis of Amino Acids" Can. J. Chem. 2001, 79, 94-104. Lien - Article - Link |
54. |
GOSSELIN, F.; TOURWE, D.; CEUSTERS, M; MEERT, T.; HEYLEN, L.; JURZAK, M.; LUBELL, W.D. "Probing Opioid Receptor-Ligand Interactions by Employment of Indolizidin-9-one Amino Acid as a Constrained Gly2-Gly3 Surrogate in a Leucine-Enkephalin Mimic" J. Peptide Res. 2001, 57,337-44. |
53. |
HALAB,L.; LUBELL, W. D. "Effect of Stereochemistry on 5-tert-Butylproline Type VI β-Turn Mimics" J. Peptide Sci. 2001, 7, 92-104. |
52. |
DAIRI, K.; KEILLOR, J.W.; LUBELL, W. D. "Solid-Phase Synthesis of Aspartic Protease Mimics" In Peptides 2000 (Proc. 26th Eur. Peptide Symp.), J. Martinez & J.-A. Fehrentz, Eds. 2001, 803-804. |
51. |
HALAB, L.; LUBELL, W. D. "Stabilization of Type VI β-Turns in Tetrapeptides" In Peptides 2000 (Proc. of the 26th Eur.Peptide Symposium), J. Martinez & J.-A. Fehrentz, Eds. 2001, 815-816. |
| 50. | BÉLEC, L.; SLANINOVA, J.; LUBELL, W. D. "Steric Interactions of Penicilamine6-5-tert-Butylproline7-Oxytocin Analogues and Their Influence on Conformation and Biological Activity" In Peptides 2000 (Proc. 26th Eur. Peptide Symp.), J. Martinez & J.-A. Fehrentz, Eds. 2001, 587-588. |
49. |
GROTH, T.; GRØTLI, M.; LUBELL, W. D.; MIRANDA, L.; MELDAL, M. "Novel concept of resin polymerization: preparation of HYDRA - a bifunctional PEG based resin by reductive amination" In Peptides 2000 (Proceedings of the 26th European Peptide Symposium), J. Martinez & J.-A. Fehrentz, Eds. 2001, 981-982. |
48. |
GRØTLI, M.; RADEMAN, J.; GROTH, T.; LUBELL, W.; MIRANDA, L.; MELDAL, M. "Surfactant Mediated Cationic and Anionic Suspension Polymerization of PEG-based Resins in Silicon Oil; Beaded SPOCC 1500 and POEPOP 1500" J. Combi. Chem. 2001, 3, 28-33. Lien - Article - Link |
2000 |
|
47. |
KHIAT, A.; FOURNIER, A.; LUBELL, W.; BOULANGER, Y. "Conformational analysis of endothelin-1 analogs with indolizidinone amino acids incorporated at the C-terminus" J. Cardiovascular Pharmacology 2000, 36 (Supp. 1), S33-S35. |
46. |
GROTH, T.; GRØTLI, M.; LUBELL, W. D.; MIRANDA, L.; MELDAL, M. H. "A Novel Hydroxy and Amine Functionalised Resin Synthesised by Reductive Amination of PEG Aldehyde and a Polyamine" J. Chem. Soc., Perkin Trans.1 2000, 4258-4264. |
45. |
MANNEKENS, E.; TOURWE, D.; LUBELL, W. D. "Efficient Synthesis of 1-Benzyloxyphenyl-3-phenylacetones" Synthesis 2000, 1214-1216. |
44. |
HALAB,L.; GOSSELIN, F.; LUBELL, W. D. "Design, Synthesis and Conformational Analysis of Azacycloalkane Amino Acids as Conformationally Constrained Probes for Mimicry of Peptide Secondary Structures" Biopolymers, Peptide Science 2000, 55, 101-122. |
43. |
WEI, L.; LUBELL, W. D. "Racemization in the Use of N-(9-(9-Phenylfluorenyl))Serine-Derived Cyclic Sulfamidates in the Synthesis of δ-Keto α-Amino Carboxylates and Prolines" Org. Lett. 2000, 2, 2595-2598. Lien - Article - Link |
42. |
BÉLEC, L.; SLANINOVA, J.; LUBELL, W. D. "Study of the Relationship between Biological Activity and Prolyl Amide Isomer Geometry in Oxytocin Using 5-tert-Butylproline to Control the Cysteine6-Proline7 Amide Equilibrium" J. Med. Chem. 2000, 43, 1448-1455. Lien - Article - Link |
41. |
GOSSELIN, F.; LUBELL, W. D. "Rigid Dipeptide Surrogates: Syntheses of Enantiopure Quinolizidinone and Pyrroloazepinone Amino Acids from a Common Diaminodicarboxylate Precursor" J. Org. Chem. 2000, 65, 2163-2171. Lien - Article - Link |
| 40. | SWARBRICK, M.E.; LUBELL, W.D. "A Stereoconvergent Approach for Synthesizing Enantiopure 5,6-Dialkylpipecolic Acids" Chirality 2000, 12, 366-373. |
39. |
RONDEAU,D; GILL, P.; CHAN, M.; CURRY, K.; LUBELL, W. D. "Synthesis and Pharmacology of New Enantiopure ∆3-4-Arylkainoids" Bioorg. Med. Chem. Lett. 2000, 10, 771-773. |
38. |
THOUIN, E; LUBELL, W. D. "Effective synthesis of enantiopure hydroxamates by displacement of oxime resine esters with hydroxylamine" Tetrahedron Lett. 2000, 41, 249-256. |
37. |
BEAUSOLEIL, E.; LUBELL, W. D. "An Examination of the Steric Effects of 5-tert-Butylproline on the Conformation of Polyproline and the Cooperative Nature of Type II to Type I Helical Interconversion" Biopolymers 2000, 53, 249-256. |
36. |
POLYAK, F.; LUBELL, W. D. "Mimicry of Peptide Back-bone and Side-Chain Functions: Syntheses of 5- and 7-Hydroxymethyl Indolizidinone Amino Acids and Indolizidinone Amino Dicarboxylate, Constrained Ser-Pro and Glu-Pro Surrogates" In Peptides: Chem., Structure and Biology, Greg Fields and George Barany, Eds; ESCOM, Leiden, The Netherlands, 2000, 150-152. |
35. |
BÉLEC, L.; SLANINOVA, J.; LUBELL, W. D. "Studying the influence of prolyl amide geometry on bioactivity with 5-tert-butylproline oxytocin analogues" In Peptides: Chem., Structure and Biology, Greg Fields and George Barany, Eds; ESCOM, Leiden, The Netherlands, 2000, 630-631. |
34. |
HALAB, L.; LUBELL, W. D. "The effects of stereochemistry and sequence on 5-tert-butylproline type VI β-turn mimics" In Peptides: Chem., Structure and Biology, Greg Fields and George Barany, Eds; ESCOM, Leiden, The Netherlands, 2000, 305-306. |
1999 |
|
33. |
HALAB, L.; LUBELL, W.D. "The Use of Steric Interactions to Control Peptide Turn Geometry. Synthesis of Type VI β-Turn Mimics with 5-tert-Butylproline" J. Org. Chem. 1999, 64, 3312-3321. Lien - Article - Link |
32. |
GOSSELIN, F.; VAN BETSBRUGGE, J.; HATAM, M.; LUBELL, W. D. "A Novel Linking-Protecting Group Strategy for Solid-Phase Organic Chemistry with Configurationally Stable α-[N-(Phenylfluorenyl)]Amino Carbonyl Compounds : Synthesis of Enantiopure Norephedrines on Solid Support" J. Org. Chem. 1999, 64, 2486-2493. Lien - Article - Link |
31. |
SWARBRICK, M.E.; GOSSELIN, F.; LUBELL, W.D. "Alkyl Substituent Effects on Pipecolyl Amide Isomer Equilibrium: Efficient Methodology for Synthesizing Enantiopure 6-Alkylpipecolic Acids and Conformational Analysis of their N-Acetyl N'-Methylamides" J. Org. Chem. 1999, 64, 1993-2002. Lien - Article - Link |
| 30. | GOSSELIN, F.; SWARBRICK, M. E.; LUBELL, W. D. "Synthesis of ε-Alkylpipecolates as Conformationally Rigid Proline Surrogates" Peptides 1998 (Proc. of the 25th Europ. Peptide Symp.), S. Bajusz & F. Hudecz, Eds; Akadémia Kiadó, Budapest, Hungary, 1999, 678-679. |
29. |
HALAB, L.; LUBELL, W. D. "Steric Effects of 5-tert-Butylproline in Dipeptide Mimics of Type VI β-Turns" In Peptides 1998 (Proceedings of the 25th European Peptide Symposium), S. Bajusz and F. Hudecz, Editors; Akadémia Kiadó, Budapest, Hungary, 1999, 356-357. |
28. |
POLYAK, F.; LUBELL, W. D. "Synthesis and Incorporation of 7-Benzyl Indolizidinone Amino Acid into Leucine Enkephalin" In Peptides 1998 (Proc. of the 25th European Peptide Symposium), S. Bajusz and F. Hudecz, Editors; Akadémia Kiadó, Budapest, Hungary, 1999, 688-689. |
27. |
GOSSELIN, F.; LUBELL, W. D. "Indolizidin-9-one Amino Acid, A New Rigid Dipeptide Turn Mimic" In Peptides 1998 (Proceedings of the 25th European Peptide Symposium), S. Bajusz and F. Hudecz, Editors; Akadémia Kiadó, Budapest, Hungary, 1999, 660-661. |
1998 |
|
26. |
GOSSELIN, F.; LUBELL, W. D. "An Olefination Entry for the Synthesis of Enantiopure α,ω-Diamino-dicarboxylates and Azabicyclo[X.Y.0]alkane Amino Acids" J. Org. Chem. 1998, 63, 7463-7471. Lien - Article - Link |
25. |
BEAUSOLEIL, E.; SHARMA, R.; MICHNICK, S.; LUBELL, W.D. "Alkyl 3-Position Substituents Retard the Isomerization of Prolyl and Hydroxyprolyl amides in water" J. Org. Chem. 1998, 63, 6572-6578. Lien - Article - Link |
24. |
POLYAK, F.; LUBELL, W.D. "Rigid Dipeptide Mimics: Synthesis of Enantiopure 5- and 7-Benzyl, and 5,7-Dibenzyl Indolizidinone Amino Acids Via Enolization and Alkylation of δ-Oxo α,ω-Di-[N-(9-(9-phenylfluorenyl))amino]azelate Esters" J. Org. Chem. 1998, 63, 5937-5949. Lien - Article - Link |
23. |
BEAUSOLEIL, E.; LUBELL, W.D. "Steric Effects of 5-tert-Butylproline on the Conformation of Polyproline" In Peptides: Chem., Structure and Biology, James P. Tam & P.T.P. Kaumaya, Eds; ESCOM, Leiden, The Netherlands, 1998, 150-151. |
1997 |
|
22. |
BEAUSOLEIL, E.; SHARMA, R.; MICHNICK, S.; LUBELL, W.D. "Steric Effects of Alkylprolines on the Conformation of N-(Acetyl)Proline N'-Methylamides" In Peptides 1996 (Proceedings of the 24th Europ. Peptide Symp.), R. Ramage & R. Epton, Eds; ESCOM, Leiden, The Netherlands, 1997,241-242. |
21. |
HANESSIAN, S.; MCNAUGHTON-SMITH, G; LOMBART, H.-G.; LUBELL, W. D. "Design and Synthesis of Conformationally Constrained Amino Acids as Versatile Scaffolds and Peptide Mimetics" Tetrahedron 1997, 53, 12789-12854. |
1996 |
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| 20. | LOMBART, H.-G.; LUBELL, W. D. "Rigid Dipeptide Mimetics. Efficient Synthesis of Enantiopure Indolizidinone Amino Acids" J. Org. Chem. 1996, 61, 9437-9446. Lien - Article - Link |
19. |
BEAUSOLEIL, E.; L'ARCHEVÊQUE, B.; BÉLEC, L.; ATFANI, M.; LUBELL, W.D. "5-tert-Butylproline" J. Org. Chem. 1996, 61, 9447-9454. Lien - Article - Link |
18. |
BEAUSOLEIL, E.; LUBELL, W.D. "Steric Effects on the Amide Rotamer Equilibrium of Prolyl Peptides. Synthesis and Conformational Analysis of N-Acetyl-5-tert-Butylproline N'-Methylamides" J. Am. Chem. Soc. 1996, 118, 12902-12908. Lien - Article - Link |
17. |
GOSSELIN, F.; DI RENZO, M.; ELLIS, T.; LUBELL, W. D. "Photoacoustic FT-IR, A Non-Destructive Method for Sensitive Spectroscopic Analysis of Solid-Phase Organic Chemistry" J. Org. Chem. 1996, 61, 7980-7981. Lien - Article - Link |
16. |
SHARMA, R.; LUBELL, W.D. "Regioselective Enolization and Alkylation of 4-Oxo-N-(9-phenylfluoren-9-yl)proline : Synthesis of Enantiopure Proline-Valine and Hydroxyproline-Valine Chimeras" J. Org. Chem. 1996, 61, 202-209. Lien - Article - Link |
15. |
LOMBART, H.-G.; LUBELL, W. D. "Use Of Azabicycloalkane Amino Acids To Stabilize b-Turn Conformations In Model Peptides And Gramicidin S" In Peptides: Chemistry, Structure and Biology, P.T.P. Kaumaya and R.S. Hodges , Editors; ESCOM Sci. Pub. B.V.: Leiden, The Netherlands, 1996, 695-696. |
1995 |
|
14. |
GILL, P.; LUBELL, W.D. "Synthesis of Enantiopure Arylkainoids; Preparation of (2S)-∆3-4-Phenylkainic Acid" J. Org. Chem. 1995, 60, 2658-2659. Lien - Article - Link |
13. |
ATFANI, M.; LUBELL, W.D. "Synthesis of (S)-2-Amino-3-(3-tert-butyl-4-isoxazol-5(2H)-one)propionic acid" J. Org. Chem. 1995, 60, 3184-3188. Lien - Article - Link |
12. |
KITAMURA, M.; TOKUNAGA, M.; PHAM, P.; LUBELL, W. D.; NOYORI, R. "Asymmetric Synthesis of α-Amino β-Hydroxy Phosphonic Acids Via BINAP–Ruthenium Catalyzed Hydrogenation" Tetrahedron Lett. 1995, 36, 5769-5772. |
11. |
LOMBART, H.-G.; LUBELL, W. D. "A Claisen Condensation Approach To Prepare Azabicycloalkane Amino Acid β-Turn Mimetics" In Peptides 1994 (Proceedings of the 23rd European Peptide Symposium), H. L. S. Maia, Ed.; ESCOM, Leiden, Netherlands, 1995, 696-697. |
1994 |
|
| 10. | LOMBART, H.-G.; LUBELL, W. D. "Synthesis of Enantiopure α-,ω-Diamino Dicarboxylates and Azabicycloalkane Amino Acids by Claisen Condensation of a-N-(phenylfluorenyl)amino Dicarboxylates" J. Org. Chem. 1994, 59, 6147-6149. Lien - Article - Link |
9. |
PHAM, T.; LUBELL, W.D. "A Practical Enantioselective Synthesis of α-Aminodicarboxylates. Preparation of Δ- and L-α-Aminoadipate, α-Aminopimelate, and α-Aminosuberate" J. Org. Chem. 1994, 59, 3676 - 3680. Lien - Article - Link |
8. |
IBRAHIM, H. H.; BEAUSOLEIL, E.; ATFANI, M.; LUBELL, W. D. "Synthesis Of 5-Alkylprolines And Their Use In The Design Of X-Proline Cis-Amide Surrogates" In Peptides: Chemistry, Structure and Biology, R.S. Hodges and J.A. Smith, Editors; ESCOM Science Publishers B.V.: Leiden, The Netherlands, 1994, 307-309. |
1993 |
|
7. |
IBRAHIM, H. H.; LUBELL, W.D. "Synthesis of Enantiopure Δ-Oxo α-Amino Esters and Prolines Via Acylation of N-Phenylfluorenylglutamate Enolates" J. Org. Chem. 1993, 58, 6438 - 6441. Lien - Article - Link |
1992-1987 |
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6. |
JAMISON, T.F.; LUBELL, W.D.; DENER, J.M.; KRISCHÉ, M.J.; RAPOPORT, H. "Synthesis of 9-Bromo-9-phenylfluorene" Org. Syn. 1992, 71, 220 - 235. |
5. |
LUBELL, W.D.; KITAMURA, M.; NOYORI, R. "Enantioselective Synthesis of β-Amino Acids Based on BINAP – Ruthenium(II) Catalyzed Hydrogenation" Tetrahedron. Asymm. 1991, 2, 543-554. |
4. |
LUBELL, W.D.; JAMISON, T.F.; RAPOPORT, H. "N-(9-Phenylfluoren-9-yl)α-Amino Ketones and α-Amino Aldehydes as Chiral Educts for the Synthesis of Optically Pure 4-Alkyl 3-Hydroxy 2-Amino Acids. Synthesis of the C-9 Amino Acid, MeBmt, Present in Cyclosporin" J. Org. Chem. 1990, 55, 3511-3522. |
3. |
LUBELL, W.D.; RAPOPORT, H. "Surrogates for Chiral Aminomalondialdehyde. Synthesis of N-(9-Phenylfluoren-9-yl)serinal and N-(9-Phenylfluoren-9-yl)vinylglycinal" J. Org. Chem. 1989, 54, 3824-3831. Lien - Article - Link |
2. |
LUBELL, W.D.; RAPOPORT, H. "α-Amino Acids as Chiral Educts for Asymmetric Products. Alkylation of N-Phenylfluorenyl α-Amino Ketones. Synthesis of α-Alkyl Substituted Carboxylic Acids" J. Am. Chem. Soc. 1988, 110, 7447-7455. Lien - Article - Link |
1. |
LUBELL, W.D.; RAPOPORT, H. "Configurational Stability of N-Protected α-Amino Aldehydes" J. Am. Chem. Soc. 1987, 109, 236-239. Lien - Article - Link |
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